Contents:Preface. List of contributors -- Spatial And Temporal Organisation Of Multiprotein Systems Of Cell Regulation And Signalling: What Can We Learn From Nhej System Of Double-Strand Break Repair?; Qian Wu -- Co-Translational Protein Processing, Folding, Targeting, And Membrane Insertion Of Newly Synthesized Proteins; D. Boehringer, N. Ban -- The Role Of Multiple Sequence Repeat Motifs In The Assembly Of Multi-Protein Complexes; D. Barford -- Cryoelectron Tomography Or Doing Structural Biology In Situ ; W. Baumeister -- Ruvbl1 And Ruvbl2 And Their Complex Proteins Implicated In Many Cellular Pathways; S. Gorynia et al -- The Structural Biology Of Muscle: Spatial And Temporal Aspects; K. Holmes.- Molecular Basis Of Allosteric Transitions: GroEL; A, Horovitz -- Cell Signalling Through Covalent Modification And Allostery; L. N. Johnson -- Combining Cryo-Em And X-Ray Crystallography To Study Membrane Protein Structure And Function; W. Kühlbrandt -- Molecular Mechanisms Of Dna Polymerase Clamp Loaders; B. Kelch et al -- Electron Microscopy Of Macromolecular Machines; Helen R. Saibil -- Assembly And Function Of The Signal Recognition Particle From Archaea; E. Sauer-Eriksson et al -- Structural Studies Of The Functional Complexes Of The 50s And 70s Ribosome, A Major Antibiotic Target; Th. A. Steitz et al -- Proteopedia: Exciting Advances In The 3d Encyclopedia Of Biomolecular Structure; J. Prilusky -- Structure Analysis Of Biological Macromolecules By Small-Angle X-Ray Scattering; D. I. Svergun -- Structural Dynamics Of The Vault Ribonucleoprotein Particle; A. Casañas -- Structural Dynamics Of Picornaviral Rdrp Complexes. Implications For The Design Of Antivirals; N. Verdaguer -- Ribosomes: Ribozymes That Survived Evolution Pressures But Is Paralyzed By Tiny Antibiotics; A.Yonath.