Contents:Preface -- Epidemiology of IGF-1 and Cancer -- Aging and Cancer: The IGF-I Connection -- Obesity, Type 2 Diabetes and Cancer -- IGF System and Breast Cancer -- The Role of Insulin-Like Growth Factor Signaling in Prostate Cancer Development and Progression -- Mouse Models of IGF-1 Deficiency -- Insulin-like Growth Factor Signaling in Pediatric Sarcomas -- Cancer Genes, Tumor Suppressors, and Regulation of IGF-1R Expression in Cancer -- Mouse Models of IGF-1R and Cancer -- Targeting the Insulin-Like Growth Factor-I Receptor in Cancer Therapy -- Targeting Insulin-like Growth Factor (IGF-1R) and Insulin Receptor Signaling by Tyrosine Kinase Inhibitors in Cancer -- Calories and Cancer: The Role of Insulin-like Growth Factor -- Cancer Cell Metabolism -- Overlaps between the Insulin and IGF-1R and Cancer -- Index.